Director, Medical Science Liaison

Company: COMPASS Pathways
Location: San Francisco
Posted on: February 19, 2026

Job Description:

Job Description Job Description Company introduction: Compass Pathways plc (Nasdaq: CMPS) is a biotechnology company dedicated to accelerating patient access to evidence-based innovation in mental health. The Company is headquartered in London, UK, with offices in New York City in the US. We focus on developing novel treatments that have the potential to improve the lives of those who are suffering with mental health conditions and who are not helped by current treatments. We are pioneering a new paradigm for treating mental health conditions focused on rapid and durable responses through the development of our investigational COMP360 synthetic psilocybin treatment, potentially a first in class treatment. COMP360 has Breakthrough Therapy designation from the US Food and Drug Administration (FDA) and has received Innovative Licensing and Access Pathway (ILAP) designation in the UK for treatment-resistant depression (TRD) due to the pressing unmet need in this area. We are currently in phase 3 for TRD, have completed phase 2 studies for both post-traumatic stress disorder (PTSD) and anorexia nervosa and are planning a further late-stage study in PTSD. We envision a world where mental health means not just the absence of illness but the ability to thrive. - Compass Pathways. Job overview: The Director, Medical Science Liaisons at Compass Pathways will lead and develop a high-performing field medical team focused on impactful scientific engagement within the neuroscience and mental health community. This role is responsible for translating Compass's medical strategy into effective field activities, overseeing MSL operations across a defined region, and ensuring consistent, high-quality scientific exchange with external stakeholders. The Director will drive execution of the national medical affairs plan, coach and mentor MSLs to enhance scientific credibility and performance, and partner closely with cross-functional teams to ensure that field insights help inform medical strategy, clinical development, and educational initiatives. At this level, the role also supports the growth of Compass's treatment-resistant depression (TRD) and post-traumatic stress disorder (PTSD) franchises by reinforcing scientific leadership, shaping medical engagement plans, and advancing relationships with key external experts and thought leaders. Location: Remote on the West Coast, USA (covering for Pacific Northwest, Southwest, Rocky Mountains). Reports to : Senior Director, Medical Science Liaisons. Roles and responsibilities: (include but not limited to) Lead, coach, and develop a high-performing MSL team within a region, setting clear expectations for scientific excellence, compliance, and professional growth Foster a culture of scientific rigor, collaboration, accountability, and continuous improvement within Field Medical Translate medical strategy into effective field execution, ensuring consistent, high-quality scientific engagement across territories Oversee territory planning, stakeholder prioritization, and deployment of field medical resources Ensure the timely collection, synthesis, and communication of actionable medical insights from the field to inform clinical development, medical strategy, and education planning. Maintain awareness of emerging science, treatment landscape developments, and competitive activity relevant to TRD and PTSD Support medical education initiatives, advisory boards, and scientific congress engagement at the regional or national level Contribute to the evolution of Medical Affairs processes, training, tools, and metrics to support a growing field medical organization Liaise cross-functionally with Clinical Development, Market Access, Government Affairs, and other internal teams to align field medical activities with organizational priorities Candidate Profile: Advanced scientific training with associated credentials (e.g., PhD, PharmD, PMHNP, MD) At least 3 years of Medical Science Liaison experience Proven field medical leader with demonstrated ability to manage projects and cross-functional relationships Preference for candidates with background/experience in neuroscience, psychiatry or psychology Experience managing and supporting direct reports required Experience in pre-commercial or early-launch environments preferred Ability to travel up to 50-75%, including overnight stays and weekends, as needed A thoughtful leader, who's highly organized and accountable Excellent verbal and written communication, listening skills, and emotional intelligence Proven experience of self-motivation, accountability, integrity & teamwork Passion for improving and transforming mental health – full alignment with Compass values Benefits & Compensation: For an overview of our benefits package and compensation information, please visit "Working at Compass". Equal opportunities: Reasonable accommodation We are committed to building a workplace where everyone's wellbeing matters. If you need reasonable accommodation during the interview process to be at your best, please let our recruiting team know. UK applicants We are proud of our commitment to diversity and equality (pursuant to the Equality Act 2010). We do not discriminate based upon race, religion or belief, colour, nationality, ethnic or national origin, gender, pregnancy or maternity, marital or civil partner status, sexual orientation, gender reassignment, age or disability. US applicants Compass Pathways is proud to be an equal opportunity employer. All employment decisions are based on business needs, job requirements, and individual qualifications, without regard to race, religion, color, national origin, sex (including pregnancy, childbirth, and related medical conditions), ethnicity, age, disability, sexual orientation, gender identity, gender expression, military service, genetic information, familial or marital status, or any other status, category, or characteristic protected by applicable law. Sponsorship: Unfortunately, we cannot sponsor employment visas and can only accept applications if you have employment rights in the country to which you are applying. Data Privacy: All data is confidential and protected by all legal and data privacy requirements, please see our recruitment Privacy Notice to learn more about how we process personal data.

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