SantarosaRecruiter Since 2001
the smart solution for Santa Rosa jobs

Head of Cell Biology Genomics

Company: AbbVie, Inc.
Location: Clearlake
Posted on: April 8, 2021

Job Description:

  • Lake County, United States of America; Illinois, United States of America
  • Research and Development
  • 1904231 Job Description About AbbVie
    AbbVie's mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women's health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com . Follow @abbvie on Twitter , Facebook , Instagram , YouTube and LinkedIn .

    The Genomics Research Center (GRC) is a center of excellence for genetics and genomics that supports both Discovery and Development. The GRC goal is to develop world class genetics and genomics research focused on finding the right targets and helping AbbVie scientists better understand not only human disease biology but also the behavior of and response to our drugs in clinical trials across all therapeutic areas. AbbVie has committed to obtaining a range of Omics data on more than 1 million participants from Genomics Medicine Ireland, FinnGen and the UKbiobank, as well as our clinical trials. Over 300,000 data sets are already in house. This leader will be responsible for building strategies and solutions to "functionalize" variants that are critical to understanding disease processes and therefore potential targets for new therapeutics across all therapeutic areas and leading at least three departments within the GRC. We have an exciting opportunity for a Senior Director, based in Lake County, Illinois.The candidate will be on the Executive Leadership Team of the GRC and play a critical role in helping to lead and shape genomics activities across AbbVie. Key Responsibilities:
    • Lead a series of teams positioned to conduct validation studies, based on results from genetic and genomic studies, that leverage cellular (cell lines and iPSCs) models, in vitro tissue systems up to whole animal systems to help investigators in therapeutic areas maximize the value.
    • Develop strategies and solutions to rapidly "functionalize" large numbers of variants implicated in various diseases across Therapeutic Areas from our different population cohorts and clinical trial cohorts.
    • Implement cellular assays to assess biological pathways and gene sets that mechanistically link the gene targets to disease(s), leveraging our extensive infrastructure, e.g. Compact SelecT automated cell culture system, SeahorseXF and Operetta cell imaging systems for cell biological work.
    • Deploy pooled and array based CRISPR technologies and libraries for whole genome screening to variant modification.
    • Represent the GRC on various discovery and clinical teams involved in a range of drug pipeline activities seeking to understand the disease process.
    • Participate in the leadership of the GRC.
    • Collaborate with scientists across different Early Discovery therapeutic areas to interpret and incorporate genetic findings into new targets or for validation of existing targets
    • Lead groups developing new models (cellular, organoids and whole animal) to validate targets of interest.
      Qualifications
      Level and compensation will be commensurate with experience. Basic:
      • MD, PhD or both with at least 10 years of industry experience in cell biology, cellular models of human disease, and functional genomics.
      • Possess a strong background in applying genomic technologies to identify genes responsible for common complex disease and rare diseases.
      • Demonstrated ability to design and lead genetic and genomic studies delivering novel findings and medically relevant gene discoveries leveraging cell-based assays.
      • Demonstrated leader of high functioning teams. Additional desired skills include:
        • Experience with multidisciplinary teams on both the basic research and clinical questions
        • Deep knowledge of translating genomic data into clinically relevant results.
        • Experience in Immunology, Neuroscience or Oncology would be a plus.
        • Experience with large-scale research projects involving next generation DNA sequencing data (e.g. whole exome and whole genome) in conjunction with results from informatics and wide array of molecular biology strategies.
        • Experience or strong knowledge of pharmacogenomics or pharmacogenetics
        • Experience with deploying iPSCs for drug discovery.
        • Strong communication skills in a collaborative environment
          Significant Work Activities
          Continuous sitting for prolonged periods (more than 2 consecutive hours in an 8 hour day)
          Travel
          Yes, 15 % of the Time
          Job Type
          Experienced
          Schedule
          Full-time
          Job Level Code
          D
          Equal Employment Opportunity
          At AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.
          As an online job seeker, you could be a target of cyber (online) thieves seeking to secure personal information from you by sending you "phishing" messages. Please be alert to and protect yourself from phishing scams. Click here to find out how you can avoid being a victim of job phishing scams.

Keywords: AbbVie, Inc., Santa Rosa , Head of Cell Biology Genomics, Other , Clearlake, California

Click here to apply!

Didn't find what you're looking for? Search again!

I'm looking for
in category
within


Other Other Jobs


Software Engineer (Security Clearance Required) - Remote
Description: Join Hired and find your dream job as a Security Software Engineer at one of 10,000 companies looking for candidates just like you.Companies on Hired apply to you, not the other way around. You'll (more...)
Company: HIRED
Location: West Sacramento
Posted on: 04/15/2021

Loan Processor
Description: If you are a Loan Processor with experience, please read on What You Need for this PositionAt Least 3 Years of Experience WIth: FHA Guidelines Desktop Underwriting USDA Guidelines Conventional Guidelines (more...)
Company: CyberCoders
Location: San Ramon
Posted on: 04/15/2021

Warehouse Package Handler
Description: Auto req ID: 271483BR br br Job Summary br br FedEx Ground is an essential business that needs people to help us support the economy, handling life-saving medications and other items that keep (more...)
Company: FedEx
Location: San Ramon
Posted on: 04/15/2021


Front-End Engineer
Description: Join Hired and find your dream job as a Front-End Engineer at one of 10,000 companies looking for candidates just like you.Companies on Hired apply to you, not the other way around. You'll receive (more...)
Company: HIRED
Location: San Ramon
Posted on: 04/15/2021

Production Worker (2nd Shift)
Description: Description:Candidates will be required to work on a production/ warehouse floor where they will be in charge of packing various food items from rice, garbanzo beans, Cinnamon, and other grains. They (more...)
Company: Aerotek
Location: Woodland
Posted on: 04/15/2021

Front-End Engineer - Remote
Description: Join Hired and find your dream job as a Front-End Engineer at one of 10,000 companies looking for candidates just like you.Companies on Hired apply to you, not the other way around. You'll receive (more...)
Company: HIRED
Location: Woodland
Posted on: 04/15/2021

Documentation Specialist I
Description: Documentation Specialist I for a temporary opportunity with Yoh's client located in Fremont, California.The Big Picture - Top Skills You Should Possess: ul li Shift: 1st, Sunday - Wednesday, 6:00am (more...)
Company: Yoh, A Day & Zimmermann Company
Location: San Ramon
Posted on: 04/15/2021

Au Pair
Description: Primary Purpose Provides care to children ages infant ----- 17 in a safe and nurturing environment that encourages their social, emotional, physical and intellectual development. Implement developmentally (more...)
Company: Bright Horizons
Location: San Ramon
Posted on: 04/15/2021

Software Engineer - Remote
Description: Join Hired and find your dream job as a Software Engineer at one of 10,000 companies looking for candidates just like you.Companies on Hired apply to you, not the other way around. You'll receive (more...)
Company: HIRED
Location: Woodland
Posted on: 04/15/2021

60761: Spec-Talent Talent Acquisition Specialist
Description: Job DescriptionJob Title: 60761: Spec-Talent AcquisitionJob Requisition Number: RC344209Locations:4075 Channel DriveWest Sacramento, California 95691Time Type: Full TimeCompensation: FXFUS 8POSITION OVERVIEW:Responsible (more...)
Company: FedEx Freight
Location: West Sacramento
Posted on: 04/15/2021

Log In or Create An Account

Get the latest California jobs by following @recnetCA on Twitter!

Santa Rosa RSS job feeds